LOCUS       KO-first_condition_ready_39483_MGI:1096335        20437 bp    dna     circular UNK 
DEFINITION  Mus musculus targeted KO-first, conditional ready, lacZ-tagged
            mutant vector Adam17 targeting project(s): 39483
ACCESSION   unknown
SOURCE      Mus musculus
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
            Sciurognathi; Muroidea; Muridae; Murinae; Mus.
COMMENT     cassette: L1L2_st1
COMMENT     design_id: 40121
COMMENT     backbone: L3L4_pZero_DTA_kan
FEATURES             Location/Qualifiers
     misc_feature    29..49
                     /note="B4 Gateway"
     promoter        85..598
                     /note="mouse phosphoglycerate kinase 1 promoter"
     CDS             612..1268
                     /note="DTA"
     misc_feature    1393..1651
                     /note="BGH pA"
     CDS             complement(2147..2941)
                     /note="KanR"
     misc_feature    4053..4073
                     /note="B3 Gateway"
     misc_feature    4079..4086
                     /note="AsiSI"
     misc_feature    1..4111
                     /note="Synthetic Backbone"
     misc_feature    4112..8417
                     /note="5 arm"
     misc_feature    8445..8469
                     /note="B1 Gateway"
     misc_feature    8482..8529
                     /note="Frt"
     intron          8530..9404
                     /note="mouse En2 intron"
     misc_feature    9402..9404
                     /note="Splice Acceptor"
     exon            9405..9451
                     /note="mouse En2 exon"
     misc_feature    9452..10129
                     /note="rat Cd4"
     misc_feature    9934..10017
                     /note="rat CD4 transmembrane region"
     gene            10138..13184
                     /gene="lacZ"
                     /note="lacZ"
     misc_feature    13198..13251
                     /note="'self-cleaving' 2A peptide"
     gene            13252..14043
                     /gene="NeoR"
                     /note="NeoR"
     misc_feature    14243..14484
                     /note="SV40 polyadenylation site"
     misc_feature    14501..14548
                     /note="Frt"
     misc_feature    14555..14588
                     /note="loxP"
     misc_feature    9419..9469
                     /note="FCHK std_st2"
     misc_feature    9419..9436
                     /note="FCHK QC prefix region"
     misc_feature    9437..9451
                     /note="FCHK QC critical region"
     misc_feature    9452..9469
                     /note="FCHK QC suffix region"
     misc_feature    14604..14624
                     /note="B2 Gateway"
     misc_feature    8418..14654
                     /note="Synthetic Cassette"
     exon            15044..15176
                     /db_xref="ENSEMBL:ENSMUSE00001035193"
                     /type="targeted"
                     /rank="2"
                     /note="target exon 1 ENSMUSE00001035193"
     misc_feature    14655..15345
                     /note="Critical Region"
     misc_feature    15369..15402
                     /note="Downstream LoxP"
     misc_feature    15346..15425
                     /note="synthetic loxP region"
     misc_feature    15426..20437
                     /note="3 arm"
ORIGIN      
        1 ccactggccg tcgttttaca ttaattaaca acttttctat acaaagttga cagataaacg
       61 gatcccctag tttgtgatag gatcgaattc taccgggtag gggaggcgct tttcccaagg
      121 cagtctggag catgcgcttt agcagccccg ctgggcactt ggcgctacac aagtggcctc
      181 tggcctcgca cacattccac atccaccggt aggcgccaac cggctccgtt ctttggtggc
      241 cccttcgcgc caccttctac tcctccccta gtcaggaagt tcccccccgc cccgcagctc
      301 gcgtcgtgca ggacgtgaca aatggaagta gcacgtctca ctagtctcgt gcagatggac
      361 agcaccgctg agcaatggaa gcgggtaggc ctttggggca gcggccaata gcagctttgc
      421 tccttcgctt tctgggctca gaggctggga aggggtgggt ccgggggcgg gctcaggggc
      481 gggctcaggg gcggggcggg cgcccgaagg tcctccggag gcccggcatt ctgcacgctt
      541 caaaagcgca cgtctgccgc gctgttctcc tcttcctcat ctccgggcct ttcgacctgc
      601 aggtcctcgc catggatcct gatgatgttg ttgattcttc taaatctttt gtgatggaaa
      661 acttttcttc gtaccacggg actaaacctg gttatgtaga ttccattcaa aaaggtatac
      721 aaaagccaaa atctggtaca caaggaaatt atgacgatga ttggaaaggg ttttatagta
      781 ccgacaataa atacgacgct gcgggatact ctgtagataa tgaaaacccg ctctctggaa
      841 aagctggagg cgtggtcaaa gtgacgtatc caggactgac gaaggttctc gcactaaaag
      901 tggataatgc cgaaactatt aagaaagagt taggtttaag tctcactgaa ccgttgatgg
      961 agcaagtcgg aacggaagag tttatcaaaa ggttcggtga tggtgcttcg cgtgtagtgc
     1021 tcagccttcc cttcgctgag gggagttcta gcgttgaata tattaataac tgggaacagg
     1081 cgaaagcgtt aagcgtagaa cttgagatta attttgaaac ccgtggaaaa cgtggccaag
     1141 atgcgatgta tgagtatatg gctcaagcct gtgcaggaaa tcgtgtcagg cgatctcttt
     1201 gtgaaggaac cttacttctg tggtgtgaca taattggaca aactacctac agagatttaa
     1261 agctctaagg taaatataaa atttttaagt gtataatgtg ttaaactact gattctaatt
     1321 gtttgtgtat tttagattcc aacctatgga actgatgaat gggagcagtg gtggaatgca
     1381 gatcctagag ctcgctgatc agcctcgact gtgccttcta gttgccagcc atctgttgtt
     1441 tgcccctccc ccgtgccttc cttgaccctg gaaggtgcca ctcccactgt cctttcctaa
     1501 taaaatgagg aaattgcatc gcattgtctg agtaggtgtc attctattct ggggggtggg
     1561 gtggggcagg acagcaaggg ggaggattgg gaagacaata gcaggcatgc tggggatgcg
     1621 gtgggctcta tggcttctga ggcggaaaga accagctggg gctcgacgcg ccgtacccag
     1681 cttttgttcc ctttagtgag ggcctgaatg gcgaatggac gcgccctgta gcggcgcatt
     1741 aagcgcggcg ggtgtggtgg ttacgcgcag cgtgaccgct acacttgcca gcgccctagc
     1801 gcccgctcct ttcgctttct tcccttcctt tctcgccacg ttcgccggct ttccccgtca
     1861 agctctaaat cgggggctcc ctttagggtt ccgatttagt gctttacggc acctcgaccc
     1921 caaaaaactt gattagggtg atggttcacg tagtgggcca tcgccctgat agacggtttt
     1981 tcgccctttg acgttggagt ccacgttctt taatagtgga ctcttgttcc aaactggaac
     2041 aacactcaac cctatctcgg tctattcttt tgatttataa gggattttgc cgatttcggc
     2101 ctattggtta aaaaatgagc tgatttaaca aaaattttaa caaaattcag aagaactcgt
     2161 caagaaggcg atagaaggcg atgcgctgcg aatcgggagc ggcgataccg taaagcacga
     2221 ggaagcggtc agcccattcg ccgccaagct cttcagcaat atcacgggta gccaacgcta
     2281 tgtcctgata gcggtccgcc acacccagcc ggccacagtc gatgaatcca gaaaagcggc
     2341 cattttccac catgatattc ggcaagcagg catcgccatg ggtcacgacg agatcctcgc
     2401 cgtcgggcat gctcgccttg agcctggcga acagttcggc tggcgcgagc ccctgatgct
     2461 cttcgtccag atcatcctga tcgacaagac cggcttccat ccgagtacgt gctcgctcga
     2521 tgcgatgttt cgcttggtgg tcgaatgggc aggtagccgg atcaagcgta tgcagccgcc
     2581 gcattgcatc agccatgatg gatactttct cggcaggagc aaggtgagat gacaggagat
     2641 cctgccccgg cacttcgccc aatagcagcc agtcccttcc cgcttcagtg acaacgtcga
     2701 gcacagctgc gcaaggaacg cccgtcgtgg ccagccacga tagccgcgct gcctcgtctt
     2761 gcagttcatt cagggcaccg gacaggtcgg tcttgacaaa aagaaccggg cgcccctgcg
     2821 ctgacagccg gaacacggcg gcatcagagc agccgattgt ctgttgtgcc cagtcatagc
     2881 cgaatagcct ctccacccaa gcggccggag aacctgcgtg caatccatct tgttcaatca
     2941 tgcgaaacga tcctcatcct gtctcttgat cagatcttga tcccctgcgc catcagatcc
     3001 ttggcggcga gaaagccatc cagtttactt tgcagggctt cccaacctta ccagagggcg
     3061 ccccagctgg caattccggt tcgcttgctg tccataaaac cgcccagtct agctatcgcc
     3121 atgtaagccc actgcaagct acctgctttc tctttgcgct tgcgttttcc cttgtccaga
     3181 tagcccagta gctgacattc atccggggtc agcaccgttt ctgcggactg gctttctacg
     3241 tgaaaaggat ctaggtgaag atcctttttg ataatctcat gaccaaaatc ccttaacgtg
     3301 agttttcgtt ccactgagcg tcagaccccg tagaaaagat caaaggatct tcttgagatc
     3361 ctttttttct gcgcgtaatc tgctgcttgc aaacaaaaaa accaccgcta ccagcggtgg
     3421 tttgtttgcc ggatcaagag ctaccaactc tttttccgaa ggtaactggc ttcagcagag
     3481 cgcagatacc aaatactgtt cttctagtgt agccgtagtt aggccaccac ttcaagaact
     3541 ctgtagcacc gcctacatac ctcgctctgc taatcctgtt accagtggct gctgccagtg
     3601 gcgataagtc gtgtcttacc gggttggact caagacgata gttaccggat aaggcgcagc
     3661 ggtcgggctg aacggggggt tcgtgcacac agcccagctt ggagcgaacg acctacaccg
     3721 aactgagata cctacagcgt gagctatgag aaagcgccac gcttcccgaa gggagaaagg
     3781 cggacaggta tccggtaagc ggcagggtcg gaacaggaga gcgcacgagg gagcttccag
     3841 ggggaaacgc ctggtatctt tatagtcctg tcgggtttcg ccacctctga cttgagcgtc
     3901 gatttttgtg atgctcgtca ggggggcgga gcctatggaa aaacgccagc aacgcggcct
     3961 ttttacggtt cctgggcttt tgctggcctt ttgctcacat gtaatacgac tcactatagg
     4021 gcgaattgga gctaggcggc cgtttatcgt gccaacttta ttatacaaag ttgcggacgc
     4081 gatcgccggc ggataacaat ttcacacagg aatgagtcct agtttgaaaa gagcaaaaat
     4141 atgtagaata tgtattcagg aaagttgaga caaaggtagg aagatagaga agttggaagg
     4201 cagtaaggaa aataggatcc ctgagtccag taggtagtgc caggtgggga actaaactta
     4261 cagcacttgg tggagaagag cagggcagag tggacttaga gaacattctc ccgctgaccc
     4321 gcctctgctt ccagagtgct gggagtcagc tgtgcagctc catgccaggc accagttacc
     4381 acttatttat tttttattga gagatttggg taggaatgca acctctgttg cagaggttgt
     4441 aggagaatgt gcccactaag ggctaaagat ctggaggtga gctgcagtgg gatgctgagg
     4501 agctgaggag cacttgctaa gaagacagta ttaggagcag taagtggctc cagtttgcct
     4561 tccaagaggg agctgttttt tattgagttg tttgtaatgg ctctaggaca tctaatttgt
     4621 aatatccagt tattaagaag aagataattg cagtggaaac acagtagcta ttttaaagtt
     4681 attttaaatg tagcaagctt catttaaaag gcacatatta tagaccatat atatatatcc
     4741 cttatttttc ttctagcccc atttttatac attaagctat tggaataggt tttgaaatcc
     4801 tcccgttgct caactttgta gataagcttt tcacttgttc ttaaaaacct gccctgacca
     4861 ggcttttaaa tactaagtag tatttaaaac tgtcctttgg aagttctgct gcttatctgt
     4921 tttccagttt agcttacctt gtttggttgt ttttaaaagc aatgaagctg aataagagtg
     4981 agctgggtga gctggatctt aaatatatga gtgttagctg taaaaaggag ccagtacacc
     5041 tgtctactat gccttactgt accgtaatta aggtggaatg caaaaagagc cctaagttga
     5101 gtgtccccac acgtttgcta tatatcagct ggttggtctc cagcagggag cattattttt
     5161 agttgtttgc ttacttgaac ttaagtaagc aaacagctaa aaagagttac tttaaataat
     5221 taaaaataat tctcttcctc tttccctttt tttttccctc ttaatggtat ggtgccaggg
     5281 gcctttgagg gcaggtggtt ctctttcttg cctagggtag ccttgaactc cagccattct
     5341 ctttcttgcc tcagctttca gtgactaaga ttaccggtag aagccgtcct gctgccaaac
     5401 ttgtttagtg gttttcagat ttgaattcac atgagacaca cctgtatggc aacataaatt
     5461 gctggacccc acagtgggaa tttttgaatg tttgtgtttc taacaagctc ctagctgctc
     5521 ctgctgctgg tgtggggagg gccacactct gaggagccat ggtccttgtc actgacagtg
     5581 aaagtacaat gttgacgtta ggtctctaag tcagcaggtg cgattgtgac actaatgaca
     5641 ctgagctcat gcagcagcct ggatcaaggc agcggccagc taaaggactg tattggcatt
     5701 tcagcattga aaagtcctgt cgtctgtgga cggcagcctg atggctcaag ctgccttgct
     5761 gagtatgttg tggtgagata gtataatgag agccaggtgt ggtggccctc acttgggagg
     5821 cggattccgg attagaaatt caaggccagc ctagggcccc gtgagataat gccacaagaa
     5881 aaagatgctg tgatgagtaa aacatggctc ctttttggtc attttctgat ctatgtgata
     5941 agacatgtcc taaccaaaag tatccaggaa aaaaagatac agagagctgt caacttcaga
     6001 gggaagaaat gccatgtttg tttgaaatgc taggaagtca aagaccagag gtagacagtc
     6061 ccaggagggc gagactattt tcacaggtgt tccaaagcat tatttcagta aagcttgagt
     6121 atttcagcct gcatggaatt ttaaaaaccc agggctgtgt tgcacttggc tttatttttc
     6181 ctttggttct ttggcacact agtggcatca gggtttgtga tagtagacac attatttagt
     6241 cttctctcag cctgtttgcc ttcatttgga gaattacagt cttgggatgg tctgtgtaga
     6301 tagtgtagta gagaaagctt gggatttttg ttgttgttgt tgttgttttt tgtttttcga
     6361 gacagggttt ctctgtatag ccctggctgt cctggaactc actttgtaga ccaggctggc
     6421 cttgaactca gaaatctgcc tgcctttgcc tcctgagtgc tgggactaaa agcgtgtgcc
     6481 accacgcccg gcccaaatgt ttactttttt actgtgtaac aataaacact agtatgggct
     6541 gctgctgttc tgaggaattc caggtccatt ggaatgattt gaatatcctt gatcgtggaa
     6601 aggaaaggag aatatcaact caggtatttt aggtagctat tatttatttt tgttatatgt
     6661 gtttgagtgt tcacatggat atatgtgcat caaatgtgta cctgctgtct gtgtaggcca
     6721 ggagagggtg tcagatcccc atgaactgga gggacacact cttgtgagtc accatgtggt
     6781 gctgggaaca gaacctgggt cctctgcaag aacagtaagc actgggtcac ctctccagtc
     6841 ccctttcaga cagttttaaa cgagactaga ggcagtattt ttaagtggaa aaccttttaa
     6901 aaagaaagaa agaaagaaag aaagaaagaa agaaagaaag aaagaaagaa agaaagaaag
     6961 aaagaaagaa agaaagaaag aaagaaaagt tcttattttg gaggggccag ggagtctgtt
     7021 ggttgaagca tgaagaggaa tggcatgtac ttactatagt agtctagttt tgaatctcat
     7081 ttgtgctttt tctcagctgg ggtcagtgca tctttgtttt cttgagtggt gacttggtct
     7141 ggtaaagcag ttggtgttgg tttccttctg aggaatcagt ccgttccctc tgcctgcacc
     7201 tactgagcag gcggatgcca atgcacctgt tggggcagca gtggtagtag tgctcctccc
     7261 agctctgggt ttggaggatg agtcttgctg acaagcctaa actggtctgg aactcaggct
     7321 ttctgcggaa gctttacttt cctggctctg gtttgcaaga aaccagaggc tgttgataca
     7381 tacatttgtt actcttctta ctaacagtcc cctgaaaaag ggttgaccat gaaagtgtta
     7441 gctcagctaa ttttatcttg gacactttaa acatgcacac tagaaatgcc ttttatttta
     7501 aagtctaagt gtatatatgg tagtctttag cgacaccaaa ttgttagttt ctaaccccag
     7561 tccatgctta ggtctctgaa tgtttaagta tgttccccca gctagattgt ttgccacgat
     7621 tcagagtgat tccttagtgc agctatttct gtattcttaa gtctgttact ccttgcccct
     7681 cccttcttcc cggagaaact gggtcatttg ttctgcagga atctaacttt ctaggtgtgg
     7741 ctgatgcttt cttcactagt tatttaactt ggcagtatct gaacctctta tgtactaaga
     7801 ctctgaactt acatctccat taagttcagg ttcagatttt tttttttgta agaatgtgat
     7861 tgttgtgctg tgcaattaag cacttcagct tattgtttga gatagttgac tattagattt
     7921 aagtgctaat accttttaaa attatttgtt tactttttat gtgtatgaat gttttgccta
     7981 tatgtaagta tgtgtggttt gtgtgttttg tgtgtgtgtg tgtgtgtttt atgccagtgg
     8041 aagtcagaag agagtgtcag atttcctgga actagattta cagatggttg ttagctgcca
     8101 tatggatgct aggaactgaa cctgggtcct ctttctctgt aagaacaagt gctcttaact
     8161 gctgatggag ctcttcagcc tctgacaacc tttagtaaag atctatttac ttttatgcta
     8221 tgaatatttt acctgtatgt ataccatgta catgtctggt gcccatgggg gtcagaggag
     8281 ggccttggat tcccctcctt gaagtgcagc tacagatggt tgtgagctgc catgtgagag
     8341 ctgggatctg aacccagatc ctctggaaga acagcaagtg ctcttcactg ctgagctacc
     8401 ttttcagcct tcgtaataag gcgcataacg ataccacgat atcaacaagt ttgtacaaaa
     8461 aagcaggctg gcgccggaac cgaagttcct attccgaagt tcctattctc tagaaagtat
     8521 aggaacttcg aaccctttcc cacaccaccc tccacacttg ccccaaacac tgccaactat
     8581 gtaggaggaa ggggttggga ctaacagaag aacccgttgt ggggaagctg ttgggagggt
     8641 cactttatgt tcttgcccaa ggtcagttgg gtggcctgct tctgatgagg tggtcccaag
     8701 gtctggggta gaaggtgaga gggacaggcc accaaggtca gccccccccc cctatcccat
     8761 aggagccagg tccctctcct ggacaggaag actgaagggg agatgccaga gactcagtga
     8821 agcctggggt accctattgg agtccttcaa ggaaacaaac ttggcctcac caggcctcag
     8881 ccttggctcc tcctgggaac tctactgccc ttgggatccc cttgtagttg tgggttacat
     8941 aggaaggggg acgggattcc ccttgactgg ctagcctact cttttcttca gtcttctcca
     9001 tctcctctca cctgtctctc gaccctttcc ctaggataga cttggaaaaa gataagggga
     9061 gaaaacaaat gcaaacgagg ccagaaagat tttggctggg cattccttcc gctagctttt
     9121 attgggatcc cctagtttgt gataggcctt ttagctacat ctgccaatcc atctcatttt
     9181 cacacacaca cacaccactt tccttctggt cagtgggcac atgtccagcc tcaagtttat
     9241 atcaccaccc ccaatgccca acacttgtat ggccttgggc gggtcatccc cccccccacc
     9301 cccagtatct gcaacctcaa gctagcttgg gtgcgttggt tgtggataag tagctagact
     9361 ccagcaacca gtaacctctg ccctttctcc tccatgacaa ccaggtccca ggtcccgaaa
     9421 accaaagaag aagaacgcag atcgcagatc tgcgggctgc agggagagtt gagatggaag
     9481 gcagagaagg ctccttcttc ccagtcctgg atcaccttct ccctaaagaa ccaaaaggtg
     9541 tctgtgcaga agtctactag caaccccaag ttccagctgt ccgaaacgct cccactcacc
     9601 cttcagatac cccaggtctc ccttcagttt gctggttctg gcaacctgac cctgactctg
     9661 gacagaggga tactgtatca ggaagtgaac ctggtggtga tgaaagtgac tcagcccgac
     9721 agcaacactt tgacctgtga ggtgatggga cccacctcac ccaagatgag actgatcttg
     9781 aagcaggaga atcaggaggc cagggtctcc aggcaggaga aagtgattca agtgcaggcc
     9841 cctgaagcag gggtgtggca atgtctactg agtgaaggtg aagaggtcaa gatggactcc
     9901 aagatccagg ttttatccaa agggttgaac cagacaatgt tcctggctgt cgtgctgggg
     9961 agcgccttca gctttctggt tttcacgggg ctctgcatcc tattctgtgt caggtgccgg
    10021 caccaacagc gccaggcagc acggatgtct cagatcaaga ggcttctcag tgagaagaag
    10081 acttgccagt gctcccaccg gatgcagaaa agccacaatc tcatatatgg gagcgatgat
    10141 cccgtcgttt tacaacgtcg tgactgggaa aaccctggcg ttacccaact taatcgcctt
    10201 gcagcacatc cccctttcgc cagctggcgt aatagcgaag aggcccgcac cgatcgccct
    10261 tcccaacagt tgcgcagcct gaatggcgaa tggcgctttg cctggtttcc ggcaccagaa
    10321 gcggtgccgg aaagctggct ggagtgcgat cttcctgagg ccgatactgt cgtcgtcccc
    10381 tcaaactggc agatgcacgg ttacgatgcg cccatctaca ccaacgtgac ctatcccatt
    10441 acggtcaatc cgccgtttgt tcccacggag aatccgacgg gttgttactc gctcacattt
    10501 aatgttgatg aaagctggct acaggaaggc cagacgcgaa ttatttttga tggcgttaac
    10561 tcggcgtttc atctgtggtg caacgggcgc tgggtcggtt acggccagga cagtcgtttg
    10621 ccgtctgaat ttgacctgag cgcattttta cgcgccggag aaaaccgcct cgcggtgatg
    10681 gtgctgcgct ggagtgacgg cagttatctg gaagatcagg atatgtggcg gatgagcggc
    10741 attttccgtg acgtctcgtt gctgcataaa ccgactacac aaatcagcga tttccatgtt
    10801 gccactcgct ttaatgatga tttcagccgc gctgtactgg aggctgaagt tcagatgtgc
    10861 ggcgagttgc gtgactacct acgggtaaca gtttctttat ggcagggtga aacgcaggtc
    10921 gccagcggca ccgcgccttt cggcggtgaa attatcgatg agcgtggtgg ttatgccgat
    10981 cgcgtcacac tacgtctgaa cgtcgaaaac ccgaaactgt ggagcgccga aatcccgaat
    11041 ctctatcgtg cggtggttga actgcacacc gccgacggca cgctgattga agcagaagcc
    11101 tgcgatgtcg gtttccgcga ggtgcggatt gaaaatggtc tgctgctgct gaacggcaag
    11161 ccgttgctga ttcgaggcgt taaccgtcac gagcatcatc ctctgcatgg tcaggtcatg
    11221 gatgagcaga cgatggtgca ggatatcctg ctgatgaagc agaacaactt taacgccgtg
    11281 cgctgttcgc attatccgaa ccatccgctg tggtacacgc tgtgcgaccg ctacggcctg
    11341 tatgtggtgg atgaagccaa tattgaaacc cacggcatgg tgccaatgaa tcgtctgacc
    11401 gatgatccgc gctggctacc ggcgatgagc gaacgcgtaa cgcgaatggt gcagcgcgat
    11461 cgtaatcacc cgagtgtgat catctggtcg ctggggaatg aatcaggcca cggcgctaat
    11521 cacgacgcgc tgtatcgctg gatcaaatct gtcgatcctt cccgcccggt gcagtatgaa
    11581 ggcggcggag ccgacaccac ggccaccgat attatttgcc cgatgtacgc gcgcgtggat
    11641 gaagaccagc ccttcccggc tgtgccgaaa tggtccatca aaaaatggct ttcgctacct
    11701 ggagagacgc gcccgctgat cctttgcgaa tacgcccacg cgatgggtaa cagtcttggc
    11761 ggtttcgcta aatactggca ggcgtttcgt cagtatcccc gtttacaggg cggcttcgtc
    11821 tgggactggg tggatcagtc gctgattaaa tatgatgaaa acggcaaccc gtggtcggct
    11881 tacggcggtg attttggcga tacgccgaac gatcgccagt tctgtatgaa cggtctggtc
    11941 tttgccgacc gcacgccgca tccagcgctg acggaagcaa aacaccagca gcagtttttc
    12001 cagttccgtt tatccgggca aaccatcgaa gtgaccagcg aatacctgtt ccgtcatagc
    12061 gataacgagc tcctgcactg gatggtggcg ctggatggta agccgctggc aagcggtgaa
    12121 gtgcctctgg atgtcgctcc acaaggtaaa cagttgattg aactgcctga actaccgcag
    12181 ccggagagcg ccgggcaact ctggctcaca gtacgcgtag tgcaaccgaa cgcgaccgca
    12241 tggtcagaag ccgggcacat cagcgcctgg cagcagtggc gtctggcgga aaacctcagt
    12301 gtgacgctcc ccgccgcgtc ccacgccatc ccgcatctga ccaccagcga aatggatttt
    12361 tgcatcgagc tgggtaataa gcgttggcaa tttaaccgcc agtcaggctt tctttcacag
    12421 atgtggattg gcgataaaaa acaactgctg acgccgctgc gcgatcagtt cacccgtgca
    12481 ccgctggata acgacattgg cgtaagtgaa gcgacccgca ttgaccctaa cgcctgggtc
    12541 gaacgctgga aggcggcggg ccattaccag gccgaagcag cgttgttgca gtgcacggca
    12601 gatacacttg ctgatgcggt gctgattacg accgctcacg cgtggcagca tcaggggaaa
    12661 accttattta tcagccggaa aacctaccgg attgatggta gtggtcaaat ggcgattacc
    12721 gttgatgttg aagtggcgag cgatacaccg catccggcgc ggattggcct gaactgccag
    12781 ctggcgcagg tagcagagcg ggtaaactgg ctcggattag ggccgcaaga aaactatccc
    12841 gaccgcctta ctgccgcctg ttttgaccgc tgggatctgc cattgtcaga catgtatacc
    12901 ccgtacgtct tcccgagcga aaacggtctg cgctgcggga cgcgcgaatt gaattatggc
    12961 ccacaccagt ggcgcggcga cttccagttc aacatcagcc gctacagtca acagcaactg
    13021 atggaaacca gccatcgcca tctgctgcac gcggaagaag gcacatggct gaatatcgac
    13081 ggtttccata tggggattgg tggcgacgac tcctggagcc cgtcagtatc ggcggaattc
    13141 cagctgagcg ccggtcgcta ccattaccag ttggtctggt gtcaggggat cccccgggag
    13201 ggcagaggaa gtcttctaac atgcggtgac gtggaggaga atcccggccc tattgaacaa
    13261 gatggattgc acgcaggttc tccggccgct tgggtggaga ggctattcgg ctatgactgg
    13321 gcacaacaga caatcggctg ctctgatgcc gccgtgttcc ggctgtcagc gcaggggcgc
    13381 ccggttcttt ttgtcaagac cgacctgtcc ggtgccctga atgaactgca ggacgaggca
    13441 gcgcggctat cgtggctggc cacgacgggc gttccttgcg cagctgtgct cgacgttgtc
    13501 actgaagcgg gaagggactg gctgctattg ggcgaagtgc cggggcagga tctcctgtca
    13561 tctcaccttg ctcctgccga gaaagtatcc atcatggctg atgcaatgcg gcggctgcat
    13621 acgcttgatc cggctacctg cccattcgac caccaagcga aacatcgcat cgagcgagca
    13681 cgtactcgga tggaagccgg tcttgtcgat caggatgatc tggacgaaga gcatcagggg
    13741 ctcgcgccag ccgaactgtt cgccaggctc aaggcgcgca tgcccgacgg cgaggatctc
    13801 gtcgtgaccc atggcgatgc ctgcttgccg aatatcatgg tggaaaatgg ccgcttttct
    13861 ggattcatcg actgtggccg gctgggtgtg gcggaccgct atcaggacat agcgttggct
    13921 acccgtgata ttgctgaaga gcttggcggc gaatgggctg accgcttcct cgtgctttac
    13981 ggtatcgccg ctcccgattc gcagcgcatc gccttctatc gccttcttga cgagttcttc
    14041 tgagcgggac tctggggttc gaaatgaccg accaagcgac gcccaacctg ccatcacgag
    14101 atttcgattc caccgccgcc ttctatgaaa ggttgggctt cggaatcgtt ttccgggacg
    14161 ccggctggat gatcctccag cgcggggatc tcatgctgga gttcttcgcc caccccccgg
    14221 atctaagctc tagataagta atgatcataa tcagccatat cacatctgta gaggttttac
    14281 ttgctttaaa aaacctccca cacctccccc tgaacctgaa acataaaatg aatgcaattg
    14341 ttgttgttaa cttgtttatt gcagcttata atggttacaa ataaagcaat agcatcacaa
    14401 atttcacaaa taaagcattt ttttcactgc attctagttg tggtttgtcc aaactcatca
    14461 atgtatctta tcatgtctgg atccgggggt accgcgtcga gaagttccta ttccgaagtt
    14521 cctattctct agaaagtata ggaacttcgt cgagataact tcgtatagca tacattatac
    14581 gaagttatgt cgagatatct agacccagct ttcttgtaca aagtggttga tatctctata
    14641 gtcgcagtag gcgggtgaaa gagagaggga gtaggtggga aggctgttca tgtgggtgcc
    14701 cacagaggcc agaagatggc tttagatccc atggagctgg agttaatagg tatttttgaa
    14761 ctgtctgatg tgggtgctgg gatttgaact caggacctca ggactgagca gcgagttaat
    14821 gctcttaaat gactgagcta tgtatctagc cactaatact tttttttttt gtttttttga
    14881 gacagggttt ctctatgtag ccttggctgt cctggaaatc actctgtaga ccaggctgtc
    14941 cttgaactca gaaatccgcc tgcctctgcc tcccaagtgc tgggactaaa ggcgtgcacc
    15001 atcaccgccc ggctttacta atactttttt acctttattt cagagaagct tgattctttg
    15061 ctctcagact acgacatcct ctccttagct aatattcagc agcactccat aaggaaaagg
    15121 gatctacagt ctgcgacaca cttagaaaca ttactaactt tttcagcttt gaaaaggtaa
    15181 ttagaattat gcattgagta atatgggaca atgtgggggt gggttttgtt ttggcaaaag
    15241 cagtaaaaaa aggtatttac agaaatctta aaatacttcg taaagatttg tacttgatga
    15301 aataacatgt catgtgtgat tgtaacatca tttaatgcct attttgagat ggcgcaacgc
    15361 aattaatgat aacttcgtat agcatacatt atacgaagtt atggtctgag ctcgccatca
    15421 gttcaccaag agtattactg atggtaacaa tgtttattga ttgaatgctt ataatacttt
    15481 atattttaaa gttttttatt cattgttatg tatatgagtg ttttgcctta atatatgtct
    15541 gtatacacta ttgtgtctag tgccctcaga ggccagaagg gggtattgta gtccctggga
    15601 ctggagttac agaggtttgt gaactgggat gctgggaatc caacctgggt tctctggaag
    15661 agcaacccat gttcttaact gctgagctat ctctcgagtg cctatttaaa aattaaaaaa
    15721 aaaaatactt tatttttact gtttacgttt gtgtctgtgt gagtatatgt gcattggtgt
    15781 gtgctaggga aggaagtgta tgtacccgag gaagccagaa gagtgatcca ttagagctgg
    15841 ggttacagga tcttgtgagc cactcgatgt gggtgctgac tctgaactga cagttggtcc
    15901 ttatgacagt taaaaaagca gtaagtaaga tgggacagga gaggtagctc tggtccagag
    15961 ctctgaatgc tcttgcaggg catccagttc gattctcagc agccccatca ggtacaagta
    16021 tacatacata agaaagaata cataaaaatc ttacttaaaa agcagtagaa gtagcctggt
    16081 ggtggtgcac acctttaatc ttagtacttg cgaggcagag gcaggcaatc tctctgagtt
    16141 tgtggctagc ctggtctaca gagtgagttc taggacaacc aggggtacac agagaaactc
    16201 tgtcttgggg aagcaaagtt gtaggagaat ataaataggc tatttttttt ttaattcagt
    16261 ggataagatt ttctcaaata aaaataaaca cacaagtaat gttaccagtg ttttttaggg
    16321 caaaaccccc agcttaagca gctgcaaaag gatcaatcca cttagtactc cagttaaaca
    16381 gacagtggtg agactcacac agtaggaaga aggggtccag agaccctcaa gttcatcttc
    16441 taggttctag catgaagttt aagtctaagc agagaaaaaa attgggtcac aggaaagaga
    16501 tacttagatt aagcagtcct ggtcaaggtg tggctctccc gtcattgtct cagttcttgt
    16561 tcattgtggg gtggtccata gaagtcctta tcagttgtta ttactttgat tctttttttt
    16621 tttaagatat atttacttat tttatatatg tgagtacatt gtagctgtac agatggttgt
    16681 gagccttcat gtggttgttg ggaattgaat tattaggacc tctgctcgct ccgacccaag
    16741 gattttttat tattatacat aagtacactg tagttgtctt cagtacacaa aagagagcat
    16801 cagatctcat tacagatggt tgtgagtcac catgtagttg ctgggatttg aactcaggac
    16861 tcggaagagc agtcagtgtt ctaacctgct gagccatctc actagcccac tcttactgga
    16921 tcatgcccca gtgtataata ataatccttc tggattattg ttttcatctt gtctggtgaa
    16981 ggtaggcatc tgtcttgtga ggttttgtat ttctggtaat acagagtact tgtgggccca
    17041 gatgaagtgc aaagattcat aagtgcctat tttagtaata aatgcatcta atctaaaaac
    17101 catgttgtca cagagaaaca gggatatagt ttactttgta gagtgttttt gtaacataaa
    17161 tagggtccca tgttttatcc ccagtacctg ctctaaacct acaaaaaacc caaaccaaac
    17221 aacaacaaaa cctgaaggaa gtatagttaa gtttttcatt tcctaagttt cccagattca
    17281 aagagctttc ttgtttgtaa attccttttt tttttaagat ttatttatta ttatatctaa
    17341 gtacactgta gctgtcttca gatgcaccag aagagggcat cagagctcat tacaggtggt
    17401 tgtgagccac catatggttg ctggaatttg aactcaggac ctttggaaga gcagtcagtg
    17461 ctcttaccca ctgagccatc tcaccagccc gaaaatttct aaaaaatttt atttttagtg
    17521 cattaagatt tttttaacct atttatttat tggtggcaag ggcatttatg ttacagctat
    17581 actacagcac atgtgtagcg atcagaggac aacttgtagg agttgttctt accttcagtg
    17641 tgtgggtccc agggatcaaa ttggggccat cagacttggc agcaagcacc ttgcctacta
    17701 agccccttca gtgcatagtt tttgcacaga ttaaaatgta tatacagagc agcattcctt
    17761 cactgtgtta atgagttcaa tcaacagcag aataaatttt ctcctgatat gaacatgtat
    17821 agaatttgtc ttgttattac tccctaaaaa atagtgtttt aaatttaacc agatttttaa
    17881 tttatttttg agacaagtct tgctgtgtag ccagccctct ctgggctaga actatctgtg
    17941 tagaccatac tggtctacca tttctttaac ttgcagaaat cttgtgcctc ctaggcacta
    18001 ggattacaag cctgtgtctc tgcacctggt tctgtgtggg actggggaac ccaggccctt
    18061 gtcccgccag gcaggctctc tgccagccat gctgtgtccc cagcctagtg ctaggttttt
    18121 accagcacat agctttcatt ttttccaaag gcaaatatct cagaatttga acatcatttc
    18181 atttgttttc tgtaaatctt gctttcacag gctttcacca tttttttcta tttgagtttg
    18241 tccttttagc tactgaattg tagtattgct taggacatta agaaattggt cagggcagga
    18301 gagatggctc actggttaag agtattgact gctctatagg tcctgagttc aattcccagc
    18361 aactacatgg tggctcacaa ccatctgtga aggggatccg atgccctctt ctagtgtgtc
    18421 tgaaggcagt gacagtgtac tcacatgcat gaaataaata aatcttaaaa aaaaaaaaaa
    18481 agaattggtc agttgttggc atatatattt tgtgcaagaa atttttaata gtatttttct
    18541 agttgccata ttcatgttat tttaaataac ttttagaatt taaatgcaga tagtaaaata
    18601 gtgattacaa atagtgtaat attgactatc tagcttccac ccaacctcaa aattgagtgt
    18661 attgtttacc aggcactgac gtggcttatc tctaattctc actattctct tcatggctgt
    18721 ttcttatgtg aaggtacatg cttatggctc atagaaatga gatagtgtgc ccacagtaca
    18781 gagctgtttg tgcacagatt ggacaacctg agctcctacc acatgtacac tgtggttgtt
    18841 gtatgcccat atatatacac ataataaata aatgcagtaa aatgtgttta gtatgtagga
    18901 gcaagagagg aggtacaaaa caagaagtga aaattgagtt tcctctctta acataaatct
    18961 gaggtggctt gtgaagtcct cacctgtgat ggggcagata cttctgtggg cctgtgcgtt
    19021 tctctcttgt gtttcacaaa tgacattaga aaatgttacc gtaagctttg cgttgtggtg
    19081 cactcttagt cccggcactg agaggcagag gcaggcagga tctgggtgag gtggggtgat
    19141 ccttgtttcc atagggaatt ccagggcggc cagggctaca ctctggggtt ataggcatgc
    19201 atcaccactg tcatgctaaa attcttattt tcaaatagca gtggaagacc aaagaattta
    19261 agccagactg cagtagattt ggatgtagct gtaagaggct gaaaagcatg gaatgagtcc
    19321 taaagggatg cgtcatgaaa aagggaactc atttaaagtt tgccttctga attttgtttc
    19381 cttgttgttc agaaatgcct agtctaaaga aatgaaaaag ctgcaaaagg ggttttaatt
    19441 gccatcctgt ctggaggttt tataaaactc agtgttcaga ttagaaaacg taaaaaacat
    19501 aagttttacc attacttggg ccttattttt accatataac agatttgtct ttttataaaa
    19561 gttgtgtgtg ttcatggtta tgaatgtgga tgtatgagct caaaaggcaa tctgaggcat
    19621 cagccctcac cagccacttt ttaaaaacaa attggtcctc acattggcat gacaagtgct
    19681 ctgtccctga gccaggctcc ccagtcctga cagcagcaga aaacccagaa tgcagttcct
    19741 gggactttcc taggaagaac attagagaca ctattccagc tcatggggct ctttaatact
    19801 gaatagggca tttgtaatag gggtgctttt cttttcaaag ttccattata agcaaagtgg
    19861 aaagaacatt aacgttaatg cctgatgtag gaggacccga ctgtggacag cagaggaatg
    19921 aacgagccaa aggtttatga aatggtgtat tgtgtttctt tctgaccatc aaaaatacct
    19981 aagcaaaact aaaattacct tgtatgctca aaaagttaat atacttgttg ttcagccggg
    20041 agtggtggca catgccttta aatcccagca cttgggaggc agaggcaggc ggatttctga
    20101 gttcgggagg cagaggcagg cggatttctg agttcgaggc cagcctggtc tacaaagtga
    20161 gttccaggac agccagggct acacagagaa accctgtctc gaaaaaccaa aaccaaccaa
    20221 acaaaacccc aaacaaacaa acaaacaaac aaaaagatac cttgttgttc tggagacagc
    20281 cccagtctgg atttcttcct ggcagtttaa agatttatgc agacccacag ggaagtaaca
    20341 tttcatattt tcaacatcat agctgacaaa atttgttcct atggctgaga tgaataacat
    20401 ttcttgcttt gcttcagtat tagtgggcac attaaaa
//