LOCUS       KO-first_condition_ready_77516:80136_MGI:2679260        23880 bp    dna     circular UNK 
DEFINITION  Mus musculus targeted KO-first, conditional ready, lacZ-tagged
            mutant vector Crb2 targeting project(s): 77516:80136
ACCESSION   unknown
SOURCE      Mus musculus
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
            Sciurognathi; Muroidea; Muridae; Murinae; Mus.
COMMENT     cassette: L1L2_Bact_P
COMMENT     design_id: 102679
COMMENT     backbone: R3R4_pBR_DTA+_Bsd_amp
FEATURES             Location/Qualifiers
     misc_feature    29..152
                     /note="R4 gateway site"
     promoter        399..911
                     /note="PGK promoter"
     CDS             925..1581
                     /note="DTA"
     misc_feature    1706..1959
                     /note="BGH pA"
     promoter        2034..2100
                     /note="EM7 promoter"
     CDS             2101..2499
                     /note="BsdR"
     CDS             complement(4193..5053)
                     /note="AmpR"
     misc_feature    5272..5395
                     /note="R3 gateway site"
     misc_feature    5401..5408
                     /note="AsiSI"
     misc_feature    1..5433
                     /note="Synthetic Backbone"
     exon            7455..7650
                     /db_xref="ENSEMBL:ENSMUSE00000254526"
                     /rank="3"
                     /note="ENSMUSE00000254526"
     exon            7734..7873
                     /db_xref="ENSEMBL:ENSMUSE00000254517"
                     /rank="4"
                     /note="ENSMUSE00000254517"
     exon            8280..8465
                     /db_xref="ENSEMBL:ENSMUSE00000254510"
                     /rank="5"
                     /note="ENSMUSE00000254510"
     exon            8675..8788
                     /db_xref="ENSEMBL:ENSMUSE00000254506"
                     /rank="6"
                     /note="ENSMUSE00000254506"
     misc_feature    5434..10716
                     /note="5 arm"
     misc_feature    10744..10768
                     /note="B1 Gateway"
     misc_feature    10781..10828
                     /note="Frt"
     intron          10829..11703
                     /note="mouse En2 intron"
     misc_feature    11701..11703
                     /note="Splice Acceptor"
     exon            11704..11876
                     /note="mouse En2 exon"
     misc_feature    11888..12481
                     /note="ECMV IRES"
     gene            12482..15542
                     /gene="lacZ"
                     /note="lacZ"
     misc_feature    15581..15824
                     /note="SV40 polyadenylation site"
     misc_feature    15828..15861
                     /note="loxP"
     promoter        15888..16407
                     /note="human beta actin promoter"
     gene            16433..17227
                     /gene="NeoR"
                     /note="NeoR"
     misc_feature    17427..17668
                     /note="SV40 polyadenylation site"
     misc_feature    17685..17732
                     /note="Frt"
     misc_feature    17739..17772
                     /note="loxP"
     misc_feature    11718..11795
                     /note="FCHK std_gpr"
     misc_feature    17788..17808
                     /note="B2 Gateway"
     misc_feature    10717..17838
                     /note="Synthetic Cassette"
     exon            18249..19121
                     /db_xref="ENSEMBL:ENSMUSE00000254500"
                     /type="targeted"
                     /rank="7"
                     /note="target exon 1 ENSMUSE00000254500"
     exon            19207..19712
                     /db_xref="ENSEMBL:ENSMUSE00000254466"
                     /type="targeted"
                     /rank="8"
                     /note="target exon 2 ENSMUSE00000254466"
     misc_feature    17839..19846
                     /note="Critical Region"
     misc_feature    19870..19903
                     /note="Downstream LoxP"
     misc_feature    19847..19926
                     /note="synthetic loxP region"
     exon            20244..20409
                     /db_xref="ENSEMBL:ENSMUSE00001206522"
                     /rank="9"
                     /note="ENSMUSE00001206522"
     exon            21289..22057
                     /db_xref="ENSEMBL:ENSMUSE00000254451"
                     /rank="10"
                     /note="ENSMUSE00000254451"
     exon            22720..22836
                     /db_xref="ENSEMBL:ENSMUSE00000254441"
                     /rank="11"
                     /note="ENSMUSE00000254441"
     exon            23565..23691
                     /db_xref="ENSEMBL:ENSMUSE00000334908"
                     /rank="12"
                     /note="ENSMUSE00000334908"
     misc_feature    19927..23880
                     /note="3 arm"
ORIGIN      
        1 ccactggccg tcgttttaca ttaattaaca actttgtata gaaaagttga acgagaaacg
       61 taaaatgata taaatatcaa tatattaaat tagattttgc ataaaaaaca gactacataa
      121 tactgtaaaa cacaacatat ccagtcacta tggcggccgc aatcgggcag cgttgggtcc
      181 tggccacggg tgcgcatgat cgtgctcctg tcgttgagga cccggctagg ctggcggggt
      241 tgccttactg gttagcagaa tgaatcaccg atacgcgagc gaacgtgaag cgactgctgc
      301 tgcaaaacgt ctgcgacctg agcaacaaca tgaatggtct tcggtttccg tgtttcgtaa
      361 agtctggaaa cgggccgcct agcgatagct gtttatcgaa ttctaccggg taggggaggc
      421 gcttttccca aggcagtctg gagcatgcgc tttagcagcc ccgctgggca cttggcgcta
      481 cacaagtggc ctctggcctc gcacacattc cacatccacc ggtaggcgcc aaccggctcc
      541 gttctttggt ggccccttcg cgccaccttc tactcctccc ctagtcagga agttcccccc
      601 cgccccgcag ctcgcgtcgt gcaggacgtg acaaatggaa gtagcacgtc tcactagtct
      661 cgtgcagatg gacagcaccg ctgagcaatg gaagcgggta ggcctttggg gcagcggcca
      721 atagcagctt tgctccttcg ctttctgggc tcagaggctg ggaaggggtg ggtccggggg
      781 cgggctcagg ggcgggctca ggggcggggc gggcgcccga aggtcctccg gaggcccggc
      841 attctgcacg cttcaaaagc gcacgtctgc cgcgctgttc tcctcttcct catctccggg
      901 cctttcgacc tgcaggtcct cgccatggat cctgatgatg ttgttgattc ttctaaatct
      961 tttgtgatgg aaaacttttc ttcgtaccac gggactaaac ctggttatgt agattccatt
     1021 caaaaaggta tacaaaagcc aaaatctggt acacaaggaa attatgacga tgattggaaa
     1081 gggttttata gtaccgacaa taaatacgac gctgcgggat actctgtaga taatgaaaac
     1141 ccgctctctg gaaaagctgg aggcgtggtc aaagtgacgt atccaggact gacgaaggtt
     1201 ctcgcactaa aagtggataa tgccgaaact attaagaaag agttaggttt aagtctcact
     1261 gaaccgttga tggagcaagt cggaacggaa gagtttatca aaaggttcgg tgatggtgct
     1321 tcgcgtgtag tgctcagcct tcccttcgct gaggggagtt ctagcgttga atatattaat
     1381 aactgggaac aggcgaaagc gttaagcgta gaacttgaga ttaattttga aacccgtgga
     1441 aaacgtggcc aagatgcgat gtatgagtat atggctcaag cctgtgcagg aaatcgtgtc
     1501 aggcgatctc tttgtgaagg aaccttactt ctgtggtgtg acataattgg acaaactacc
     1561 tacagagatt taaagctcta aggtaaatat aaaattttta agtgtataat gtgttaaact
     1621 actgattcta attgtttgtg tattttagat tccaacctat ggaactgatg aatgggagca
     1681 gtggtggaat gcagatccta gagctcgctg atcagcctcg actgtgcctt ctagttgcca
     1741 gccatctgtt gtttgcccct cccccgtgcc ttccttgacc ctggaaggtg ccactcccac
     1801 tgtcctttcc taataaaatg aggaaattgc atcgcattgt ctgagtaggt gtcattctat
     1861 tctggggggt ggggtggggc aggacagcaa gggggaggat tgggaagaca atagcaggca
     1921 tgctggggat gcggtgggct ctatggcttc tgaggcggaa agaaccagct ggggctcgag
     1981 atccactagt tctagcctcg aggctagagc ggccgagttt atcctcgagc acgtgttgac
     2041 aattaatcat cggcatagta tatcggcata gtataatacg acaaggtgag gaactaaacc
     2101 atggccaagc ctttgtctca agaagaatcc accctcattg aaagagcaac ggctacaatc
     2161 aacagcatcc ccatctctga agactacagc gtcgccagcg cagctctctc tagcgacggc
     2221 cgcatcttca ctggtgtcaa tgtatatcat tttactgggg gaccttgtgc agaactcgtg
     2281 gtgctgggca ctgctgctgc tgcggcagct ggcaacctga cttgtatcgt cgcgatcgga
     2341 aatgagaaca ggggcatctt gagcccctgc ggacggtgcc gacaggtgct tctcgatctg
     2401 catcctggga tcaaagccat agtgaaggac agtgatggac agccgacggc agttgggatt
     2461 cgtgaattgc tgccctctgg ttatgtgtgg gagggctaag cacttcgtgg ccgaggagca
     2521 ggactgagaa ttccccggaa gtcagcgccc tgcaccatta tgttccggat ctgcatcgca
     2581 ggatgctgct ggctaccctg tggaacacct acatctgtat taacgaagcg ctggcattga
     2641 ccctgagtga tttttctctg gtcccgccgc atccataccg ccagttgttt accctcacaa
     2701 cgttccagta accgggcatg ttcatcatca gtaacccgta tcgtgagcat cctctctcgt
     2761 ttcatcggta tcattacccc catgaacaga aatccccctt acacggaggc atcagtgacc
     2821 aaacaggaaa aaaccgccct taacatggcc cgctttatca gaagccagac attaacgctt
     2881 ctggagaaac tcaacgagct ggacgcggat gaacaggcag acatctgtga atcgcttcac
     2941 gaccacgctg atgagcttta ccgcagctgc ctcgcgcgtt tcggtgatga cggtgaaaac
     3001 ctctgacaca tgcagctccc ggagacggtc acagcttgtc tgtaagcgga tgccgggagc
     3061 agacaagccc gtcagggcgc gtcagcgggt gttggcgggt gtcggggcgc agccatgacc
     3121 cagtcacgta gcgatagcgg agtgtatact ggcttaacta tgcggcatca gagcagattg
     3181 tactgagagt gcaccatatg cggtgtgaaa taccgcacag atgcgtaagg agaaaatacc
     3241 gcatcaggcg ctcttccgct tcctcgctca ctgactcgct gcgctcggtc gttcggctgc
     3301 ggcgagcggt atcagctcac tcaaaggcgg taatacggtt atccacagaa tcaggggata
     3361 acgcaggaaa gaacatgtga gcaaaaggcc agcaaaaggc caggaaccgt aaaaaggccg
     3421 cgttgctggc gtttttccat aggctccgcc cccctgacga gcatcacaaa aatcgacgct
     3481 caagtcagag gtggcgaaac ccgacaggac tataaagata ccaggcgttt ccccctggaa
     3541 gctccctcgt gcgctctcct gttccgaccc tgccgcttac cggatacctg tccgcctttc
     3601 tcccttcggg aagcgtggcg ctttctcata gctcacgctg taggtatctc agttcggtgt
     3661 aggtcgttcg ctccaagctg ggctgtgtgc acgaaccccc cgttcagccc gaccgctgcg
     3721 ccttatccgg taactatcgt cttgagtcca acccggtaag acacgactta tcgccactgg
     3781 cagcagccac tggtaacagg attagcagag cgaggtatgt aggcggtgct acagagttct
     3841 tgaagtggtg gcctaactac ggctacacta gaaggacagt atttggtatc tgcgctctgc
     3901 tgaagccagt taccttcgga aaaagagttg gtagctcttg atccggcaaa caaaccaccg
     3961 ctggtagcgg tggttttttt gtttgcaagc agcagattac gcgcagaaaa aaaggatctc
     4021 aagaagatcc tttgatcttt tctacggggt ctgacgctca gtggaacgaa aactcacgtt
     4081 aagggatttt ggtcatgaga ttatcaaaaa ggatcttcac ctagatcctt ttaaattaaa
     4141 aatgaagttt taaatcaatc taaagtatat atgagtaaac ttggtctgac agttaccaat
     4201 gcttaatcag tgaggcacct atctcagcga tctgtctatt tcgttcatcc atagttgcct
     4261 gactccccgt cgtgtagata actacgatac gggagggctt accatctggc cccagtgctg
     4321 caatgatacc gcgagaccca cgctcaccgg ctccagattt atcagcaata aaccagccag
     4381 ccggaagggc cgagcgcaga agtggtcctg caactttatc cgcctccatc cagtctatta
     4441 attgttgccg ggaagctaga gtaagtagtt cgccagttaa tagtttgcgc aacgttgttg
     4501 ccattgctgc aggcatcgtg gtgtcacgct cgtcgtttgg tatggcttca ttcagctccg
     4561 gttcccaacg atcaaggcga gttacatgat cccccatgtt gtgcaaaaaa gcggttagct
     4621 ccttcggtcc tccgatcgtt gtcagaagta agttggccgc agtgttatca ctcatggtta
     4681 tggcagcact gcataattct cttactgtca tgccatccgt aagatgcttt tctgtgactg
     4741 gtgagtactc aaccaagtca ttctgagaat agtgtatgcg gcgaccgagt tgctcttgcc
     4801 cggcgtcaac acgggataat accgcgccac atagcagaac tttaaaagtg ctcatcattg
     4861 gaaaacgttc ttcggggcga aaactctcaa ggatcttacc gctgttgaga tccagttcga
     4921 tgtaacccac tcgtgcaccc aactgatctt cagcatcttt tactttcacc agcgtttctg
     4981 ggtgagcaaa aacaggaagg caaaatgccg caaaaaaggg aataagggcg acacggaaat
     5041 gttgaatact catactcttc ctttttcaat attattgaag catttatcag ggttattgtc
     5101 tcatgagcgg atacatattt gaatgtattt agaaaaataa acaaataggg gttccgcgca
     5161 catttccccg aaaagtgcca cctgacgtct aagaaaccat tattatcatg acattaacct
     5221 ataaaaatag gcgtatcacg aggccctttc gtcttcaaga aaattgtcga ccatagtgac
     5281 tggatatgtt gtgttttaca gtattatgta gtctgttttt tatgcaaaat ctaatttaat
     5341 atattgatat ttatatcatt ttacgtttct cgttcaactt tattatacaa agttgcggac
     5401 gcgatcgccg gcggataaca atttcacaca ggacatcttt gccctcttgg tatctgaata
     5461 tctgtgcagg tgagacttct tgtcccagcc atttgcatat atatggttgc tctaagggtg
     5521 ctctgagtcc ttgcttgtgt cataatcggt gtatgcttct gtgggaattg tctgtgtgtc
     5581 tgtcagcagg caagtgagca ctgtctatgc agcagtcctc cgaatgtgat gtgagcaggc
     5641 agctttgcgt gactcatttc cctcctgctc ccagcagggt gggggagttg ggattccagg
     5701 ccgcctgggc ctggctctcc ctggcacaga ggataggagt ggggcaggag ggtcatggga
     5761 aggaggagtc ctggggctgg ctggacaggg aagtagggag ggctccagct ggggtcagct
     5821 ggctcctgag cccccatgac aaaacctact taggtggcag gggaaaggct gtggacgcct
     5881 acactgacag gacctgcctc ataaatcccc acacctggag attctccatc tccctctgtc
     5941 tctaccccta tccaggggag ggccaacatg tactctgggt ttccccagag gcatgggaat
     6001 tcctaggtag aaccagaaac ttccagtttt aaaaaaatta ttattattat tattattatt
     6061 attattatta ttatatgtaa gtacactgta gctgtcttca gacactccag aagagggcat
     6121 cagattttgt tacggatggt tgtgagccac catgtggctg ctgggatttg aactcaggac
     6181 ctttggaaga gcagtcggtg cttttatccg ctgagccatc tctccagccc cctgaacttc
     6241 cagttttaaa gtcaagacag catagggatt ggtgacccta ctccagtgtg tcctgtccag
     6301 agtggccctc ttctgtgggg ttccttcctc acatccttct ccaagctacc agtgatcttc
     6361 tgaaccgcac tgctgagctc ctaggttggt tgcccttttc attgctgtgg ttaaatactt
     6421 aacaagaagt aagtaaagca aggacgggta tacttgtggg gatgttgtcc gtcataagga
     6481 agagtcacct ggtcacattg tgtcctctga ggctggcgct ctgactgctg tcttcctttt
     6541 gtttgtttgt ttttccccct gcttgtattc aatccaggac ctcagtcctg gggatggtgc
     6601 tccccagact cagggtggat cctctttctt cagtcgaacc cccctgtaaa ctcccttaca
     6661 gatatagcca gaggtctctc ctctggaggg ttccaaatct ggtcaaggtg gctgaccata
     6721 aagatccact attattatcc ctaccaacag cttaatttta aaaaaatatt taattatgtc
     6781 atgtgtatgc gggtactaga agaggcaccc gggtgagagg attctagaaa tgctatctga
     6841 acatcttcac gaaagctaaa ccaagcaggt ctgctcttag ggtaggtgtg aactgcttaa
     6901 agcgggtgct gggaacggag ctctggtcct ctggaagagc aggaagctct ctttagagat
     6961 gagccctctc caggccccaa acctgacctt tcttgatggg cagaagtctg attgggctct
     7021 agtacctgat gccctcacgc ctttctccgc cactctcccc aggttctgtc ttttctccat
     7081 ctttccccca gggcattatg cctctgcctc aagagggatg ccaccaactg tcatcactgg
     7141 ccttattcag ctttcaaaaa gctgttcctg aagaagcctg ttcccagcac cctagaacag
     7201 accttggctc ctgccctaac aggatctagc tgtctctctt attgaggtca acattattaa
     7261 acagtagcct tttccggacc caccccgcgg tgggactgtc agggcaagga gggtcttctt
     7321 gtttctttct ggtctatgga cagcatttcc tctgaaagag cggaacatat gggtaactgg
     7381 agcagactgg ggctgctggt tgggcccctt ttgcccctct agatgtggtc tccatgtctc
     7441 ttgtccctgt ccaggcgtga cctgtgaggc cgaggtggac gagtgctcgt cagcgccctg
     7501 cctgcacgga ggctcgtgcc tggacggtgt gggttcctac cgctgcgtgt gcgcgccggg
     7561 atacgccggt gcgaactgtc agctggacgt ggacgagtgc cagagccagc cgtgcgcgca
     7621 cggtggcgtg tgtcacgacc tggtcaacgg gtgagccctt ggcggggtgc cctggcggcg
     7681 gggaggtggg ctgcgggatg tgcacgcgct cagctcccgc ccgcccacgc cagtttccgg
     7741 tgcgactgcg cggacacggg ttacgaaggc gcgcgctgcg agcaggaggt gctggagtgc
     7801 gcctctgcgc cctgcgcgca caacgcgtcc tgcctcgacg gcttccggag cttccgctgc
     7861 ctctgctggc caggtgtgtg cgcgcctgcc gtgttccccc aaccccgaac actctgtgtg
     7921 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgcc aggtgtgaag
     7981 ccgtgtgcat gtgtgagtgc agcctgggcc ctctgacacc tgcagtttcc tgatctgcaa
     8041 acagggttgc taacagcacc tgccccttgg gttgcagtga ggagtggcga tgtacctggc
     8101 acacaagaag ggtgtctgaa tgttagtata aagaattcgt agcaattggt agcttgctat
     8161 tactagtccc tgttgtccct ctgtcagtat ctgcatcctg atgtccctgt tcgccctggg
     8221 ttggcttagg tcatggaggg gaagctgcct agacacttgt gcttcctgat gtcttccagg
     8281 cttcagtgga gagcggtgcg aagtggatga ggacgaatgt gcatcgggcc cctgtcaaaa
     8341 tgggggccag tgcttgcagc gctctgaccc gaccttgtac gggggtgttc aggccatctt
     8401 cccgggagcc ttcagcttca gccacgccgc tggcttcctt tgcagctgtc ctctgggctt
     8461 tgctggtgag ttacctgctg gagaagcact cagccagggt ctagaacccc aaggatggat
     8521 ccagcctggc caatgcctga gtccataccc tcctctctct ctttctcatg gatctcaatc
     8581 tccccagttg taaaatggac ccttttggtt ctggtctgac tctgagggtg caggcagccg
     8641 tcacagagga gctatttatt tatttatttt acagggaatg actgcagcat ggatgtggat
     8701 gagtgtgcct cagggccgtg cctcaatgga ggtagctgcc aggacctgcc caatggtttc
     8761 cagtgctact gccaggatgg atacacaggt gcttggctgg ggtggctctg gcatggaggt
     8821 gatatggttc cttttggctg aatgtggatt gatgcatact ggaaatgagg ctaaaggtgg
     8881 ccatggtggc acaggtgaca gctgaggtgg gggtgctgag ccagaactcc aactttgtga
     8941 aaggggagaa actggtcagt ttgagtacag tcaggaggaa agggtggagt gggtggtacc
     9001 aaggctgcca ggtgaccctc tgccttggag aatgttggct ggtgacttca gccctgtaag
     9061 tactgtctgt gaagccagga ccatctgggg gtgagggtgg ggggacaagg gactaacccc
     9121 aagagagggg cctggactgg agtcagaact ggggctcatt tatggatgta tggtggtcgg
     9181 ggccctgaac tccgctatca aatcaaagag ggacagagcc ttagttcaag acagaaggag
     9241 gcagcactgg gtgcaggcac atgccttcag aaggacacac tttggctcta gggggctgtg
     9301 tctgttgtca gtggctggag tgtgaaagtt ctcctggcaa aaaggcccgg gaactgcaca
     9361 cagattttcc ctctctagtg tccctgcccc cactggaatg tgggtggcac tcccccacac
     9421 gtagcattcc tgcctagctc ttttccctgc aggtgtctgg aggcattttc ctttgcttgg
     9481 ggaagggact ggagatacat tccctctctc ctgtcttgga cactcaaaca tattggggct
     9541 cactgcctcc ccctgcccat gttgggtggc ccatgccctc tgcactgttc ctattgcttg
     9601 agcccctccc ttccatatcc tcctgcaatg gcccactcct ccatagtctc acaagggtta
     9661 ccacgcccat ctcatggaca tggcagtgaa gcctggaggg ggcgtcataa acagtgtcta
     9721 tgggaacctg gatccttcca attaaacagt gagtgacagg gagggggagc tctgagttca
     9781 gagtcctggg ggagcgatcc tagctgtgag gctgggctct ctgcccagcc tcctttgaga
     9841 caccagaagg ctctggactg gaaggtcagc ctggaattcc tgagttggct cagaagaact
     9901 caggcaggcc agactgggag ccctgttcct aagccttggt gcctctgtag gtgacgatgg
     9961 gactgtgggt gctgggccct tttctgggga gcctgtggct cttggcaggt aggaggactg
    10021 gggtgtcttg aaggaagaat ttacagcggg tgcctggtga ttgtgaggag gatggtatag
    10081 gtgtgtgggc tgatctattc tcacggaccc ctcctggcct gggtctgtac ggttgaggtg
    10141 tggggtgaga atggcctctg gttgtgttgt ggaggatctg gctgaactgt ggttgctctt
    10201 tggcctcttg actgtgaaag ggaagatggg ctggcacctt cccaggcagc gtccttgggc
    10261 acaccccagg gtagagggac ggaggagtga gccctggggt gctcagtgtg ttccaggtgt
    10321 attgccatgg ctgtcccata tctacaaagg ctctgccaag ccctttcact gggcaccaag
    10381 gacagattca ggctccagag ggaaactagg gttctgggga gccctgtttg agcaatggtg
    10441 ggattgggtc tttgagctga tctggcagcc atcggggcac ctacctttag aagttcctct
    10501 ccacctgtct ccagagtaat cagaggtctc ttcccaaggt gtcattgggc tgtgctcctt
    10561 tgctgcacat gacccagcca ctcacctgca aaccttctct gtgagggcaa gcttgaaccc
    10621 tctgtgggct ctgaatgacc aggaggagtt tgaaaatagt aagggaagtc gaggcatgac
    10681 tttccaggaa atacttagaa taagagcaag ttcaagaagg cgcataacga taccacgata
    10741 tcaacaagtt tgtacaaaaa agcaggctgg cgccggaacc gaagttccta ttccgaagtt
    10801 cctattctct agaaagtata ggaacttcga accctttccc acaccaccct ccacacttgc
    10861 cccaaacact gccaactatg taggaggaag gggttgggac taacagaaga acccgttgtg
    10921 gggaagctgt tgggagggtc actttatgtt cttgcccaag gtcagttggg tggcctgctt
    10981 ctgatgaggt ggtcccaagg tctggggtag aaggtgagag ggacaggcca ccaaggtcag
    11041 cccccccccc ctatcccata ggagccaggt ccctctcctg gacaggaaga ctgaagggga
    11101 gatgccagag actcagtgaa gcctggggta ccctattgga gtccttcaag gaaacaaact
    11161 tggcctcacc aggcctcagc cttggctcct cctgggaact ctactgccct tgggatcccc
    11221 ttgtagttgt gggttacata ggaaggggga cgggattccc cttgactggc tagcctactc
    11281 ttttcttcag tcttctccat ctcctctcac ctgtctctcg accctttccc taggatagac
    11341 ttggaaaaag ataaggggag aaaacaaatg caaacgaggc cagaaagatt ttggctgggc
    11401 attccttccg ctagctttta ttgggatccc ctagtttgtg ataggccttt tagctacatc
    11461 tgccaatcca tctcattttc acacacacac acaccacttt ccttctggtc agtgggcaca
    11521 tgtccagcct caagtttata tcaccacccc caatgcccaa cacttgtatg gccttgggcg
    11581 ggtcatcccc ccccccaccc ccagtatctg caacctcaag ctagcttggg tgcgttggtt
    11641 gtggataagt agctagactc cagcaaccag taacctctgc cctttctcct ccatgacaac
    11701 caggtcccag gtcccgaaaa ccaaagaaga agaaccctaa caaagaggac aagcggcctc
    11761 gcacagcctt cactgctgag cagctccaga ggctcaaggc tgagtttcag accaacaggt
    11821 acctgacaga gcagcggcgc cagagtctgg cacaggagct cggtacccgg aagatctgga
    11881 ctctagagaa ttccgcccct ctccctcccc cccccctaac gttactggcc gaagccgctt
    11941 ggaataaggc cggtgtgcgt ttgtctatat gttattttcc accatattgc cgtcttttgg
    12001 caatgtgagg gcccggaaac ctggccctgt cttcttgacg agcattccta ggggtctttc
    12061 ccctctcgcc aaaggaatgc aaggtctgtt gaatgtcgtg aaggaagcag ttcctctgga
    12121 agcttcttga agacaaacaa cgtctgtagc gaccctttgc aggcagcgga accccccacc
    12181 tggcgacagg tgcctctgcg gccaaaagcc acgtgtataa gatacacctg caaaggcggc
    12241 acaaccccag tgccacgttg tgagttggat agttgtggaa agagtcaaat ggctctcctc
    12301 aagcgtattc aacaaggggc tgaaggatgc ccagaaggta ccccattgta tgggatctga
    12361 tctggggcct cggtgcacat gctttacatg tgtttagtcg aggttaaaaa acgtctaggc
    12421 cccccgaacc acggggacgt ggttttcctt tgaaaaacac gatgataagc ttgccacaac
    12481 catggaagat cccgtcgttt tacaacgtcg tgactgggaa aaccctggcg ttacccaact
    12541 taatcgcctt gcagcacatc cccctttcgc cagctggcgt aatagcgaag aggcccgcac
    12601 cgatcgccct tcccaacagt tgcgcagcct gaatggcgaa tggcgctttg cctggtttcc
    12661 ggcaccagaa gcggtgccgg aaagctggct ggagtgcgat cttcctgagg ccgatactgt
    12721 cgtcgtcccc tcaaactggc agatgcacgg ttacgatgcg cccatctaca ccaacgtgac
    12781 ctatcccatt acggtcaatc cgccgtttgt tcccacggag aatccgacgg gttgttactc
    12841 gctcacattt aatgttgatg aaagctggct acaggaaggc cagacgcgaa ttatttttga
    12901 tggcgttaac tcggcgtttc atctgtggtg caacgggcgc tgggtcggtt acggccagga
    12961 cagtcgtttg ccgtctgaat ttgacctgag cgcattttta cgcgccggag aaaaccgcct
    13021 cgcggtgatg gtgctgcgct ggagtgacgg cagttatctg gaagatcagg atatgtggcg
    13081 gatgagcggc attttccgtg acgtctcgtt gctgcataaa ccgactacac aaatcagcga
    13141 tttccatgtt gccactcgct ttaatgatga tttcagccgc gctgtactgg aggctgaagt
    13201 tcagatgtgc ggcgagttgc gtgactacct acgggtaaca gtttctttat ggcagggtga
    13261 aacgcaggtc gccagcggca ccgcgccttt cggcggtgaa attatcgatg agcgtggtgg
    13321 ttatgccgat cgcgtcacac tacgtctgaa cgtcgaaaac ccgaaactgt ggagcgccga
    13381 aatcccgaat ctctatcgtg cggtggttga actgcacacc gccgacggca cgctgattga
    13441 agcagaagcc tgcgatgtcg gtttccgcga ggtgcggatt gaaaatggtc tgctgctgct
    13501 gaacggcaag ccgttgctga ttcgaggcgt taaccgtcac gagcatcatc ctctgcatgg
    13561 tcaggtcatg gatgagcaga cgatggtgca ggatatcctg ctgatgaagc agaacaactt
    13621 taacgccgtg cgctgttcgc attatccgaa ccatccgctg tggtacacgc tgtgcgaccg
    13681 ctacggcctg tatgtggtgg atgaagccaa tattgaaacc cacggcatgg tgccaatgaa
    13741 tcgtctgacc gatgatccgc gctggctacc ggcgatgagc gaacgcgtaa cgcgaatggt
    13801 gcagcgcgat cgtaatcacc cgagtgtgat catctggtcg ctggggaatg aatcaggcca
    13861 cggcgctaat cacgacgcgc tgtatcgctg gatcaaatct gtcgatcctt cccgcccggt
    13921 gcagtatgaa ggcggcggag ccgacaccac ggccaccgat attatttgcc cgatgtacgc
    13981 gcgcgtggat gaagaccagc ccttcccggc tgtgccgaaa tggtccatca aaaaatggct
    14041 ttcgctacct ggagagacgc gcccgctgat cctttgcgaa tacgcccacg cgatgggtaa
    14101 cagtcttggc ggtttcgcta aatactggca ggcgtttcgt cagtatcccc gtttacaggg
    14161 cggcttcgtc tgggactggg tggatcagtc gctgattaaa tatgatgaaa acggcaaccc
    14221 gtggtcggct tacggcggtg attttggcga tacgccgaac gatcgccagt tctgtatgaa
    14281 cggtctggtc tttgccgacc gcacgccgca tccagcgctg acggaagcaa aacaccagca
    14341 gcagtttttc cagttccgtt tatccgggca aaccatcgaa gtgaccagcg aatacctgtt
    14401 ccgtcatagc gataacgagc tcctgcactg gatggtggcg ctggatggta agccgctggc
    14461 aagcggtgaa gtgcctctgg atgtcgctcc acaaggtaaa cagttgattg aactgcctga
    14521 actaccgcag ccggagagcg ccgggcaact ctggctcaca gtacgcgtag tgcaaccgaa
    14581 cgcgaccgca tggtcagaag ccgggcacat cagcgcctgg cagcagtggc gtctggcgga
    14641 aaacctcagt gtgacgctcc ccgccgcgtc ccacgccatc ccgcatctga ccaccagcga
    14701 aatggatttt tgcatcgagc tgggtaataa gcgttggcaa tttaaccgcc agtcaggctt
    14761 tctttcacag atgtggattg gcgataaaaa acaactgctg acgccgctgc gcgatcagtt
    14821 cacccgtgca ccgctggata acgacattgg cgtaagtgaa gcgacccgca ttgaccctaa
    14881 cgcctgggtc gaacgctgga aggcggcggg ccattaccag gccgaagcag cgttgttgca
    14941 gtgcacggca gatacacttg ctgatgcggt gctgattacg accgctcacg cgtggcagca
    15001 tcaggggaaa accttattta tcagccggaa aacctaccgg attgatggta gtggtcaaat
    15061 ggcgattacc gttgatgttg aagtggcgag cgatacaccg catccggcgc ggattggcct
    15121 gaactgccag ctggcgcagg tagcagagcg ggtaaactgg ctcggattag ggccgcaaga
    15181 aaactatccc gaccgcctta ctgccgcctg ttttgaccgc tgggatctgc cattgtcaga
    15241 catgtatacc ccgtacgtct tcccgagcga aaacggtctg cgctgcggga cgcgcgaatt
    15301 gaattatggc ccacaccagt ggcgcggcga cttccagttc aacatcagcc gctacagtca
    15361 acagcaactg atggaaacca gccatcgcca tctgctgcac gcggaagaag gcacatggct
    15421 gaatatcgac ggtttccata tggggattgg tggcgacgac tcctggagcc cgtcagtatc
    15481 ggcggaattc cagctgagcg ccggtcgcta ccattaccag ttggtctggt gtcaaaaata
    15541 ataataaccg ggcagggggg atctaagctc tagataagta atgatcataa tcagccatat
    15601 cacatctgta gaggttttac ttgctttaaa aaacctccca cacctccccc tgaacctgaa
    15661 acataaaatg aatgcaattg ttgttgttaa cttgtttatt gcagcttata atggttacaa
    15721 ataaagcaat agcatcacaa atttcacaaa taaagcattt ttttcactgc attctagttg
    15781 tggtttgtcc aaactcatca atgtatctta tcatgtctgg atccggaata acttcgtata
    15841 gcatacatta tacgaagtta tgtttaaacg gcgcgccccg gaattcgcct tctgcaggag
    15901 cgtacagaac ccagggccct ggcacccgtg cagaccctgg cccaccccac ctgggcgctc
    15961 agtgcccaag agatgtccac acctaggatg tcccgcggtg ggtggggggc ccgagagacg
    16021 ggcaggccgg gggcaggcct ggccatgcgg ggccgaaccg ggcactgccc agcgtgggcg
    16081 cgggggccac ggcgcgcgcc cccagccccc gggcccagca ccccaaggcg gccaacgcca
    16141 aaactctccc tcctcctctt cctcaatctc gctctcgctc tttttttttt tcgcaaaagg
    16201 aggggagagg gggtaaaaaa atgctgcact gtgcggcgaa gccggtgagt gagcggcgcg
    16261 gggccaatca gcgtgcgccg ttccgaaagt tgccttttat ggctcgagcg gccgcggcgg
    16321 cgccctataa aacccagcgg cgcgacgcgc caccaccgcc gagaccgcgt ccgccccgcg
    16381 agcacagagc ctcgcctttg ccgatcctct agagtcgaga tccgccgcca ccatgattga
    16441 acaagatgga ttgcacgcag gttctccggc cgcttgggtg gagaggctat tcggctatga
    16501 ctgggcacaa cagacaatcg gctgctctga tgccgccgtg ttccggctgt cagcgcaggg
    16561 gcgcccggtt ctttttgtca agaccgacct gtccggtgcc ctgaatgaac tgcaggacga
    16621 ggcagcgcgg ctatcgtggc tggccacgac gggcgttcct tgcgcagctg tgctcgacgt
    16681 tgtcactgaa gcgggaaggg actggctgct attgggcgaa gtgccggggc aggatctcct
    16741 gtcatctcac cttgctcctg ccgagaaagt atccatcatg gctgatgcaa tgcggcggct
    16801 gcatacgctt gatccggcta cctgcccatt cgaccaccaa gcgaaacatc gcatcgagcg
    16861 agcacgtact cggatggaag ccggtcttgt cgatcaggat gatctggacg aagagcatca
    16921 ggggctcgcg ccagccgaac tgttcgccag gctcaaggcg cgcatgcccg acggcgagga
    16981 tctcgtcgtg acccatggcg atgcctgctt gccgaatatc atggtggaaa atggccgctt
    17041 ttctggattc atcgactgtg gccggctggg tgtggcggac cgctatcagg acatagcgtt
    17101 ggctacccgt gatattgctg aagagcttgg cggcgaatgg gctgaccgct tcctcgtgct
    17161 ttacggtatc gccgctcccg attcgcagcg catcgccttc tatcgccttc ttgacgagtt
    17221 cttctgagcg ggactctggg gttcgaaatg accgaccaag cgacgcccaa cctgccatca
    17281 cgagatttcg attccaccgc cgccttctat gaaaggttgg gcttcggaat cgttttccgg
    17341 gacgccggct ggatgatcct ccagcgcggg gatctcatgc tggagttctt cgcccacccc
    17401 ccggatctaa gctctagata agtaatgatc ataatcagcc atatcacatc tgtagaggtt
    17461 ttacttgctt taaaaaacct cccacacctc cccctgaacc tgaaacataa aatgaatgca
    17521 attgttgttg ttaacttgtt tattgcagct tataatggtt acaaataaag caatagcatc
    17581 acaaatttca caaataaagc atttttttca ctgcattcta gttgtggttt gtccaaactc
    17641 atcaatgtat cttatcatgt ctggatccgg gggtaccgcg tcgagaagtt cctattccga
    17701 agttcctatt ctctagaaag tataggaact tcgtcgagat aacttcgtat agcatacatt
    17761 atacgaagtt atgtcgagat atctagaccc agctttcttg tacaaagtgg ttgatatctc
    17821 tatagtcgca gtaggcggtg agagcctggt aggcctagac tatgacagtc tcgaatacca
    17881 aggtgagtgg ctgggtcata tgcagcaaag gtgtatagcc aggtgacacc ttgggaagag
    17941 acttctggtt actctggaga tgggtgtgga gaaacttctg aaggcagctg acctggaggc
    18001 tgccaggttt atcagagcaa gaagcatggg gtggaagaag aggtggaacc agggagtacc
    18061 ttcccaagtc aggcccacag ggcatggaga cttatcagac atggccaggg aagggaaccc
    18121 agggtggggg tggggcgggc acctggtgtg taggtgccga ggtcagcacc accatgaggc
    18181 atgtgagctc tggttggaga ttctggctcg ggcttgatgt gctgaccctt ggctgatcgc
    18241 ccctttaggc ctgacatgtc aggaagatat ggatgaatgc cagtcggaac catgcctgca
    18301 tggtggaacc tgcagcgaca ctgtagcagg ctacatctgc cagtgccctg aggcctgggg
    18361 tggacatgac tgttctgtgc agctcacagg ctgccagggc catacctgcc cactggctgc
    18421 cacctgcatc cccaccttca agtctggcct ccacggttac ttctgccgct gcccaccggg
    18481 gacctatggg cctttctgtg gccagaatac gaccttctcg gttgtgtctg ggagttctgt
    18541 gtggggattg gtgccagctg ctgcctccct gggtctggca ctgagatttc gtaccaccct
    18601 gcttgccgga accctggcta ctctcaaaga cactcgggac agcttggagc tggttctggt
    18661 gggggccgtg ctccaagcca cactctcgag acatggcact gcggtgctca tccttacact
    18721 gcctgaccta gccttaaatg atgggcattg gcaccaggtg gaagtgacgc tccacctggg
    18781 aaccctggag ctgcggctct ggcacgaggg ctgccctggc cagctctgtg tggcctctgg
    18841 tccggtggct acaggcccta cagcctcggt ggcctctggg cctccgggat cctactccat
    18901 ctatctgggc ggcggggtct ttgccggctg cttccaggat gtgcgtgtgg aagggcacct
    18961 tctgctgcct gaggagctca agggaactgt gcttctgggt tgtgagcgca gggaaccttg
    19021 ccagcctctg ccttgtgccc atggaggggc ctgcgtggac ctgtggactc acttccgctg
    19081 cgactgcccg agaccttacc gtggagccac atgcactgat ggtgaggggt tagcaggtgg
    19141 ggaggtagcg taaatgctgg gcccctaagc ctgctggcct cacaccagtg ctgtttctcc
    19201 ctacagaggt tcctgctgcc acttttggct tgggtggagc cacgagctca gcctcttttc
    19261 tgctccacca actaggccca aacctcaccg tgtcattttt cctccgcacc cgcgaacctg
    19321 ccggcctgtt gctccagttt gccaatgatt cagttgcgag cctgactgtg ttcctgagtg
    19381 agggccagat ccgggctgag gggctgggtc accctgctgt ggtcctccct gggcgctggg
    19441 atgatggact cccccacttg gtgatgctca gctttgggcc tgaccagctg caggacctgg
    19501 gccagcggct gtatgtgggt gggaggttct accctgatga cacccagctc tggggtgggc
    19561 ccttccgagg ctgtctccag gacctacaac tcaacagcat ccacctcccc ttcttctctt
    19621 ccccgatgga gaactcaagt tggcccagtg aactggaagc tggccagtcc tccaacctca
    19681 cccagggttg tgtctctgag gacacgtgca atgtgagtgg cttggagaga gtccttagct
    19741 aggatctgtg ctgtgacata gggcaagctg aggctcaaga cagccacatg agctgctcac
    19801 attcctgtca ccagaatggc agatggcagt gccccatctc ctccctgaga tggcgcaacg
    19861 caattaatga taacttcgta tagcatacat tatacgaagt tatggtctga gctcgccatc
    19921 agttcatttt tccttcccat ggtccctttt gtatcagtct cagatggcat cctgacccag
    19981 acagaggatg ggcctcagcc tttctatagc tactgtttgg ccgaaagagg catgggggtt
    20041 cattagctgg aataacctac tacgagctag actagcctct ttagtggctg ggcccttgga
    20101 ccagtggctt cacctttctg ggcctactat ctcatctgta atgtaggggt ggtgacgggt
    20161 ttccctcaac tctgtgatgt ggtggtcttg ggggtggggc actgctttta tgagtgctca
    20221 ttggtgtcct gactcttctg tagcccaatc cctgtttcaa tggtggcacg tgccacgtca
    20281 cctggaatga cttctactgc acctgctccg agaacttcac ggggcccacc tgtgcccagc
    20341 agcgatggtg ccccaggcag ccatgcctgc ctcctgccac ctgtgaggag gttccagatg
    20401 gctttgtgtg tgagtttgtg tcctgggtgc tgggtacgga agatggttag agatccctta
    20461 gggtttatgg gatgttgggt ggtggaccag gaatgccaac agccccaata tggtgggtta
    20521 ctgcattctg agaaacactc ttagggaagg tgagcatatg ctggggtttc taaggcaact
    20581 tcaagggagc cacaggagag gaaggagtgt gaggcatgtg tgaggtttta aagttcctat
    20641 ggacagctga aacacaaggt tactaaaagt gctgcacgag atagaatttg aagcccacca
    20701 agtagctcag agaccaaggg gtctcatgtt gctcaggcta gccctgaact caccatgtag
    20761 caaagggtga tcttgatctg aacttgtgat tctcctgcct ctacttcccc agtttaggga
    20821 ctatggatat gggcccctac accccatttg ttgggtgcta gggatggaac ccaaagcctc
    20881 ctacaagcta ggcagtctac caaccgaagc tactctgcca gccttacaga aggtgaggag
    20941 gagaaggata tgactggacc agcacctgtg tgcagtgaag agcgagcctc cttcagggag
    21001 gaggggagca ggttagattt aggaggagct aagattatta atatgtctag ggccttcaag
    21061 gtagcaggta ttgtggtccc cctaggacta ccccggaact gattccctcc caggaggaga
    21121 atgcataagg ggtggaagag ggagctgcag tttctgagat caggtgacag gtgggtgact
    21181 gccctggtca acagttatgg attgtggacc ctaccacctg aatgcctggg gacagggtgg
    21241 tgtaggagaa gtctggcagg tcatttccca gcggctctct ctctgcaggt gtggccgagg
    21301 ccacgttccg cgagggccct cctgctgtgt tcacaggcca caacgtgtcc tcatcgctca
    21361 gcgggctcac cctggccttc cgcacgcgcg actccgaggc tgggctactg cgcgccgtct
    21421 ccgccgcagg tgcccactcc aatatctggt tggcggtgcg caacggctcg ctggcaggag
    21481 atgtggcggg ttcggtgctg cccgcgcccg ggccgcgcgt ggccgacggc gcctggcatc
    21541 gcgtgcgcct agcccgggag ttcccacagg ccgctgcctc gcgctggctg ctgtggctgg
    21601 acggcgcggc gacacccgtg gccttgcacg gcttgggcgg cgacctgggc tttctgcagg
    21661 gtccgggtgc agtgcctctg ctactggctg agaacttcac gggctgcctg ggccgcgtgg
    21721 cacttggcga cttcccgtta cccttggcgc caccgcggtc tggcacggtg tctggggcgc
    21781 gcgagcactt cgtggcctgg cccgggtctc cggccgtgag tctcggctgc cgtggcggac
    21841 ccgtatgttc accctcgccc tgcctgcacg gtggcgcctg ccgcgacctc ttcgacgcct
    21901 ttgcttgctc ctgcggcccc gcctgggaag gaccccgctg cgagatccgc gctgacccat
    21961 gtcgctccac tccctgtgtc cggggccaat gccatgcgcg ccccgacggc cgcttcgagt
    22021 gtcgctgccc tccgggcttc tccggcccgc gctgcaggtg cgggtgacaa ggggacctga
    22081 cctgggcata gcagtgggta gagatgactg ctgatttacc gtgggtggag tttggaggga
    22141 aaaagttctt catagcttgt tcagtttggt gtccataaag ataaaataca agccgggcgt
    22201 ggtggtgcac gcctttaatc ccagcacctg ggaggcagag gcaggcggat ttctgagttc
    22261 gaggccagcc tggtctacaa agtgggttcc aggacagcca gggctataca gagaaaccct
    22321 gtcttaaaaa aaaaaaaaaa aaaaaaagac aaaatacagg ttataatagt tggcaaaatt
    22381 tgaatttcag gacgatgttg tggcttgggt agaattagga gggcaggacg aatcagggag
    22441 catggtttgc agcaagctgc ctttgaaact cccgtttcct tccggtccag agctgtctag
    22501 ctctcctctc tcctcatgtt tagcaactgt tttgcgctgc cctttaaagt cagcacgaat
    22561 caaaggcctc agctcttgtg gagttggggg aagcggcaga atgacagccc tgcgttcctt
    22621 tgcttcctgg ggaaggctgt tgaaggcagg cctgcattcc ccagagagca ccactatggc
    22681 cagctcccag cacctcactg gacttgcttt tctctgcagg ttgcctgtcc tgcctcaggg
    22741 atgcaacctc aactccacat gcaaggatgg cgccccttgt gaaggcggcc ccttaggcac
    22801 caactgcagt tgccaggaag gtcttgctgg cctcaggtgg gtctggagac cagggcctgt
    22861 ggtgttgact gggagcttgc ccctgggacg cccagcctgg gcgggagaaa tgaggtcctc
    22921 cttgtcttct tcccattgac ttaagtgcca gatccatcag tatcttttgg ttcttttagg
    22981 acttcccaga ccattatctg ttaggcagac actggctggg cagtaactgt cacccagttt
    23041 cttccttttt tctttgtttt tttattttta tttattttta ttattttttt ttaggcaggg
    23101 tttcattatg tagctgactg tctctggaac ttaatctgta gaccaggctg gcctcaaact
    23161 caagagattc acctgcctct gccttcaaat gctgggatta aaggcatgca cgaccactgc
    23221 tgacacaccc agtttctcaa agcccgttgg tccttaatgg acatggccaa aatgcaactt
    23281 ctaggcccct aggaggtgtt agttggcatc cctgtcctgc agcattatct ccccctcccc
    23341 cacacacaat ggagtaggag ccttctcagc ccatgaaccc tgggcacaag gggagtgggt
    23401 aggagatggg taccctcacc ctcagctctg gtcacttggc aaggctgggc caagcaggag
    23461 cagggtctgg ataaaccttg atgctggagg tggggaccag ctaggggaat aggaggcagc
    23521 cgtgggtggg aggactttgc gttctcagcc gttgtctctt ccagatgtca gagtctcgac
    23581 aaaccctgtg aagccagccc ttgcttgaat gggggcactt gccgggtggc cagtggcata
    23641 tttgaatgta cttgcagtgc aggattctct ggccagttct gtgaagtggt ggtgagtggt
    23701 acccagggct gggtggcaag gcctctttag accttagcaa gaggacagtg ggcagggagg
    23761 acttgtggcc tttgtggatt tgacagtgga caggctttgc tgagggtggg gagagaatac
    23821 ttaggccctt tctagtaccc aatgtagggg ttattttcac cttagggaga gttgagggag
//